# kaal:position:2026-07-31-4922

**Affirmed position.** LFA-1 and Mac-1 integrins bind to the serine/threonine-rich domain of thrombomodulin. should be assessed against Kaal's source-bound claim that Although aggregate venture capital sector data arguably only confirms what media reporting already showed for 2005 to 2015, the venture capital data, especially examined granularly, may provide earlier signals for regulators to identify areas of prospective regulatory need. The current metadata indicates a plausible connection through dynamic regulation, but the defensible response is a qualification until the source text confirms agreement, scope, methods, and limitations.

**Status.** affirmed  **Published.** 2026-07-31

**Holds when.**

- granular rather than aggregate examination of the venture capital data
- areas of increasingly disruptive innovation
- External evidence level: abstract indexed.
- Mapping review tier: ambiguity triage before claim review.
- The literature-to-claim mapping remains explicitly ambiguous and should not be treated as a settled equivalence.

**Current debate.** LFA-1 and Mac-1 integrins bind to the serine/threonine-rich domain of thrombomodulin.: https://www.semanticscholar.org/paper/9fc68197196a36caf0eb6a16a7ebdffb03122ae2

**Extends.** kaal:claim:2808132-040: https://wulfkaal.github.io/claims/2808132-040

**Scholarly basis.** Wulf A. Kaal, Erik P.M. Vermeulen, How to Regulate Disruptive Innovation - From Facts to Data (2016). SSRN: https://ssrn.com/abstract=2808132

**Source PDF sha256.** `3515f2317ed9c1d33ae55d70467cdf1f6c4e350065ea6a887d5d7619599ad7d2`

**Evidence level.** abstract indexed

**Mapping review tier.** ambiguity triage before claim review

**Mapping confidence.** 0.2134  **Mapping ambiguous.** true

**Topics.** innovation, dynamic-regulation

**Provenance.** Affirmed in historical-backfill:2026-07-31:phase-0020 at https://kaal-signal-desk.wulf577462.chatgpt.site/#review.

**Record type.** This is a dated commentary position that extends a scholarly corpus claim. It is not a verbatim claim extracted from the paper.

**Canonical form.** This markdown file is the canonical hashed representation of the position.