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 "identifier": "kaal:position:2026-07-31-5428",
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 "name": "Historical 4158135214B5A156B0Bb",
 "text": "C9orf72/ALFA-1 controls TFEB/HLH-30-dependent metabolism through dynamic regulation of Rag GTPases should be assessed against Kaal's source-bound claim that Rulemaking via code is not itself a cure for static regulation, because coded solutions are subject to natural flaws such as bugs and cannot evolutionarily change protocols, making them another stable and presumptively optimal attempt. The current metadata indicates a plausible connection through dynamic regulation, but the defensible response is a qualification until the source text confirms agreement, scope, methods, and limitations.",
 "author": {
  "@type": "Person",
  "name": "Wulf A. Kaal",
  "identifier": "https://orcid.org/0009-0008-7840-1847"
 },
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 "dateModified": "2026-07-31",
 "creativeWorkStatus": "Affirmed",
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  "dynamic-regulation",
  "governance-design"
 ],
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  "decentralized rulemaking via code without dynamic elements",
  "External evidence level: abstract indexed.",
  "Mapping review tier: ambiguity triage before claim review.",
  "The literature-to-claim mapping remains explicitly ambiguous and should not be treated as a settled equivalence."
 ],
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  "name": "C9orf72/ALFA-1 controls TFEB/HLH-30-dependent metabolism through dynamic regulation of Rag GTPases",
  "url": "https://www.semanticscholar.org/paper/d29ff09fd2f432f1fc7f1c4d60bf4e8f53815ac8"
 },
 "extends": {
  "identifier": "kaal:claim:3441904-033",
  "url": "https://wulfkaal.github.io/claims/3441904-033",
  "citation": "Wulf A. Kaal, Blockchain-Based Corporate Governance (2019). SSRN: https://ssrn.com/abstract=3441904",
  "paper": "Blockchain-Based Corporate Governance",
  "authors": [
   "Wulf A. Kaal"
  ],
  "year": "2019",
  "ssrn": "https://ssrn.com/abstract=3441904",
  "source_pdf_sha256": "e6b562527f7f19accaa35491db0a0db168b6a936755e1dca424e9f30bee7a815"
 },
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   "@id": "https://wulfkaal.github.io/claims/3441904-033"
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   "name": "C9orf72/ALFA-1 controls TFEB/HLH-30-dependent metabolism through dynamic regulation of Rag GTPases",
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  }
 ],
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 "canonicalForm": "https://wulfkaal.github.io/positions/2026-07-31-5428.md",
 "candidateId": "kaal:response-candidate:2026-07-31:749dba864e9447b0",
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 "reviewTier": "ambiguity triage before claim review",
 "mappingConfidence": 0.2064,
 "mappingAmbiguous": true,
 "mappingMethod": "idf-weighted multi-field mapping v1",
 "mappingWhyRelevant": "Shared high-information concepts: dynamic, regulation, evolutionarily. Scope: decentralized rulemaking via code without dynamic elements.",
 "sourceProvenance": {
  "source": "Semantic Scholar",
  "api": "https://api.semanticscholar.org/graph/v1/paper/search/bulk",
  "query": "dynamic regulation",
  "queryId": "concept:516a267369f9",
  "page": 7,
  "sourceRank": 6127,
  "retrievedAt": "2026-07-31T13:58:24.892Z",
  "citationCount": 21,
  "venue": "PLoS Genetics",
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