{
 "@context": "https://schema.org",
 "@type": "Claim",
 "@id": "https://wulfkaal.github.io/positions/2026-07-31-6769",
 "identifier": "kaal:position:2026-07-31-6769",
 "additionalType": "https://wulfkaal.github.io/positions/schema.json#AffirmedPositionClaim",
 "name": "Streaming Abstract 528 Restricted Proteasome Heterogeneity Promotes Premature Hear 38Bc670382",
 "text": "Abstract 528: Restricted Proteasome Heterogeneity Promotes Premature Heart Failure and Deterioration of Associated Protein Levels Upon Continuous β-Adrenergic Stimulation presents the following source proposition: The dynamic regulation of proteasome composition and function during cardiac remodeling has been of high interest. This proposition is pertinent to Kaal's source-bound claim that The shock conditions that trigger calls for rulemaking have typically not been analyzed or absorbed systematically, so rulemaking under those conditions is associated with high levels of incomplete information. The proposed response is an extension: the relationship should remain limited to the retrieved source proposition and the mapped Kaal claim unless fuller source review supports a broader conclusion.",
 "author": {
  "@type": "Person",
  "name": "Wulf A. Kaal",
  "identifier": "https://orcid.org/0009-0008-7840-1847"
 },
 "datePublished": "2026-07-31",
 "dateModified": "2026-07-31",
 "creativeWorkStatus": "Affirmed",
 "responseType": "extension",
 "keywords": [
  "dynamic-regulation",
  "economics",
  "historical-response",
  "scholarly-literature",
  "semantic-scholar"
 ],
 "scope_conditions": [
  "The response is limited to the retrieved source proposition and mapped Kaal claim unless fuller source review supports a broader conclusion.",
  "External evidence level: abstract indexed.",
  "Mapping review tier: moderate-confidence claim review.",
  "Primary mapping confidence: 0.381.",
  "The source-to-claim mapping remains explicitly ambiguous and is published with that limitation."
 ],
 "currentDebate": {
  "name": "Abstract 528: Restricted Proteasome Heterogeneity Promotes Premature Heart Failure and Deterioration of Associated Protein Levels Upon Continuous β-Adrenergic Stimulation",
  "url": "https://www.semanticscholar.org/paper/0f0ad8acbeec9c9a12b825c9235e5436ffa49282"
 },
 "extends": {
  "identifier": "kaal:claim:2273857-018",
  "url": "https://wulfkaal.github.io/claims/2273857-018",
  "citation": "Wulf A. Kaal, Dynamic Regulation of the Financial Services Industry (2013). SSRN: https://ssrn.com/abstract=2273857",
  "paper": "Wulf A. Kaal, Dynamic Regulation of the Financial Services Industry",
  "authors": [
   "Wulf A. Kaal"
  ],
  "year": "2013",
  "ssrn": "https://ssrn.com/abstract=2273857",
  "source_pdf_sha256": "e7cb3dea40593135acc99a9b00690138fe01020514ebf388f5140e1b0e59e82a"
 },
 "isBasedOn": [
  {
   "@id": "https://wulfkaal.github.io/claims/2273857-018"
  },
  {
   "@type": "CreativeWork",
   "name": "Abstract 528: Restricted Proteasome Heterogeneity Promotes Premature Heart Failure and Deterioration of Associated Protein Levels Upon Continuous β-Adrenergic Stimulation",
   "url": "https://www.semanticscholar.org/paper/0f0ad8acbeec9c9a12b825c9235e5436ffa49282"
  }
 ],
 "batch_id": "kaal-review:2026-07-31:streaming-etl-0006",
 "review_provenance": "https://kaal-signal-desk.wulf577462.chatgpt.site/#review",
 "publicationStatus": "public",
 "recordTypeNote": "Dated commentary position extending a scholarly corpus claim. Not a verbatim claim extracted from the paper.",
 "isPartOf": {
  "@id": "https://wulfkaal.github.io/positions/index.json"
 },
 "version": "1.0",
 "canonical_url": "https://wulfkaal.github.io/positions/2026-07-31-6769",
 "canonicalForm": "https://wulfkaal.github.io/positions/2026-07-31-6769.md",
 "candidateId": "kaal:response-draft:2026-07-31:6c11d355aefa54e1f0b4",
 "evidenceLevel": "abstract indexed",
 "reviewTier": "moderate-confidence claim review",
 "mappingConfidence": 0.381,
 "mappingAmbiguous": true,
 "mappingMethod": "idf-weighted multi-field mapping v1",
 "mappingWhyRelevant": "Shared high-information concepts: abstract, associated, levels, dynamic, regulation, been, high. Scope: rulemaking triggered by an unabsorbed shock.",
 "sourceProvenance": {
  "source": "semantic-scholar",
  "sourceRecordId": "0f0ad8acbeec9c9a12b825c9235e5436ffa49282",
  "queryId": "concept:516a267369f9",
  "queryText": "dynamic regulation",
  "canonicalUrl": "https://www.semanticscholar.org/paper/0f0ad8acbeec9c9a12b825c9235e5436ffa49282",
  "doi": "10.1161/res.125.suppl_1.528",
  "externalIds": {
   "MAG": "2980680280",
   "DOI": "10.1161/res.125.suppl_1.528",
   "CorpusId": 208557752,
   "SemanticScholar": "0f0ad8acbeec9c9a12b825c9235e5436ffa49282"
  },
  "retrievedAt": "2026-07-31T13:58:13.360Z",
  "providerPage": 1,
  "rawObservationSha256": "01fc598d3a8338763d7fa485f86b7ff4564d083a07bb6c883f1e6d9d741d83f2",
  "inputSnapshotSha256": "96a846999aefd65306457ebd7971f1abef182a04b39a927618f8460274d795ab",
  "inputLine": 2638,
  "chunkId": "semantic-scholar-00011",
  "workId": "work:doi:10.1161/res.125.suppl_1.528",
  "workAuthors": [
   "F. Trogisch",
   "F. Koser",
   "A. Jungmann",
   "O. Müller",
   "M. Hecker",
   "O. Drews"
  ],
  "workPublishedAt": "2019-08-02",
  "identityKeys": [
   "doi:10.1161/res.125.suppl_1.528",
   "semantic-scholar:0f0ad8acbeec9c9a12b825c9235e5436ffa49282",
   "url:https://www.semanticscholar.org/paper/0f0ad8acbeec9c9a12b825c9235e5436ffa49282",
   "title:117b6f9517906f53ed2a081b",
   "proposition:30eaa5584a32bab4a2db6d9117eb98a19fc80b20afc6fd084e7d10b085abdef7"
  ],
  "sourceProposition": "The dynamic regulation of proteasome composition and function during cardiac remodeling has been of high interest.",
  "sourcePropositionSha256": "121648fd98d2026c5a73d6875344958b225f03a266ec53be36cf84645b6e8d73",
  "sourcePropositionIndex": 1,
  "claimMappings": [
   {
    "claimId": "kaal:claim:2273857-018",
    "claimUrl": "https://wulfkaal.github.io/claims/2273857-018",
    "rank": 1,
    "confidence": 0.381,
    "method": "idf-weighted multi-field mapping v1",
    "whyRelevant": "Shared high-information concepts: abstract, associated, levels, dynamic, regulation, been, high. Scope: rulemaking triggered by an unabsorbed shock.",
    "ambiguous": true
   },
   {
    "claimId": "kaal:claim:2834531-009",
    "claimUrl": "https://wulfkaal.github.io/claims/2834531-009",
    "rank": 2,
    "confidence": 0.3557,
    "method": "idf-weighted multi-field mapping v1",
    "whyRelevant": "Shared high-information concepts: abstract, associated, levels, dynamic, regulation, high. Scope: age of continuous disruptive innovation; existing rulemaking framework.",
    "ambiguous": true
   },
   {
    "claimId": "kaal:claim:2267560-038",
    "claimUrl": "https://wulfkaal.github.io/claims/2267560-038",
    "rank": 3,
    "confidence": 0.3323,
    "method": "idf-weighted multi-field mapping v1",
    "whyRelevant": "Shared high-information concepts: abstract, dynamic, regulation, during, interest. Scope: during and after crises.",
    "ambiguous": true
   },
   {
    "claimId": "kaal:claim:2267560-037",
    "claimUrl": "https://wulfkaal.github.io/claims/2267560-037",
    "rank": 4,
    "confidence": 0.3307,
    "method": "idf-weighted multi-field mapping v1",
    "whyRelevant": "Shared high-information concepts: abstract, failure, dynamic, regulation, interest. Scope: review source claim scope.",
    "ambiguous": true
   },
   {
    "claimId": "kaal:claim:2740477-036",
    "claimUrl": "https://wulfkaal.github.io/claims/2740477-036",
    "rank": 5,
    "confidence": 0.3305,
    "method": "idf-weighted multi-field mapping v1",
    "whyRelevant": "Shared high-information concepts: abstract, associated, levels, dynamic, regulation. Scope: industry level venture capital investment data is available.",
    "ambiguous": true
   }
  ]
 },
 "userAffirmation": "I affirm batch kaal-review:2026-07-31:streaming-etl-0006, SHA-256 d724cb4e85d4ecdf4e8488b6b1c8ed999688fe58732ad5a50c5c197c25427f43, as written and authorize publication of all 250 response claims on my canonical property, preserving their evidence levels, ambiguity labels, provenance, and the unchanged 5,033 scholarly claims.",
 "sha256": "bf2902840762e4a35ba17d6cb7c98e256d3127f8e814e53a74925fbeaf25522e"
}
