{
 "@context": "https://schema.org",
 "@type": "Claim",
 "@id": "https://wulfkaal.github.io/positions/2026-07-31-6776",
 "identifier": "kaal:position:2026-07-31-6776",
 "additionalType": "https://wulfkaal.github.io/positions/schema.json#AffirmedPositionClaim",
 "name": "Streaming Abstract A053 Dynamic Regulation Of Pyruvate Carboxylase Is Required For 10Bacc9531",
 "text": "Abstract A053: Dynamic regulation of pyruvate carboxylase is required for immune evasion and pulmonary metastasis presents the following source proposition: In contrast, depletion of PC in tumor cells promotes primary tumor growth. This proposition is pertinent to Kaal's source-bound claim that Indirect regulation lets hedge funds preserve the opacity their strategies require, on the condition that their counterparties rather than the funds become the primary regulatory targets. The proposed response is an extension: the relationship should remain limited to the retrieved source proposition and the mapped Kaal claim unless fuller source review supports a broader conclusion.",
 "author": {
  "@type": "Person",
  "name": "Wulf A. Kaal",
  "identifier": "https://orcid.org/0009-0008-7840-1847"
 },
 "datePublished": "2026-07-31",
 "dateModified": "2026-07-31",
 "creativeWorkStatus": "Affirmed",
 "responseType": "extension",
 "keywords": [
  "private-funds",
  "dynamic-regulation",
  "historical-response",
  "scholarly-literature",
  "semantic-scholar"
 ],
 "scope_conditions": [
  "The response is limited to the retrieved source proposition and mapped Kaal claim unless fuller source review supports a broader conclusion.",
  "External evidence level: abstract indexed.",
  "Mapping review tier: moderate-confidence claim review.",
  "Primary mapping confidence: 0.3684.",
  "The source-to-claim mapping remains explicitly ambiguous and is published with that limitation."
 ],
 "currentDebate": {
  "name": "Abstract A053: Dynamic regulation of pyruvate carboxylase is required for immune evasion and pulmonary metastasis",
  "url": "https://www.semanticscholar.org/paper/2e2336e76af165ca51be7702fa689b667363356f"
 },
 "extends": {
  "identifier": "kaal:claim:3405660-022",
  "url": "https://wulfkaal.github.io/claims/3405660-022",
  "citation": "Kaal, Indirect Regulation of Hedge Funds (2019). SSRN: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3405660",
  "paper": "Kaal, Indirect Regulation of Hedge Funds",
  "authors": [
   "Wulf A. Kaal"
  ],
  "year": "2019",
  "ssrn": null,
  "source_pdf_sha256": "cf507b1833071765bc13a5605f38c2591582eca85f40869e38b6ff075c04d29d"
 },
 "isBasedOn": [
  {
   "@id": "https://wulfkaal.github.io/claims/3405660-022"
  },
  {
   "@type": "CreativeWork",
   "name": "Abstract A053: Dynamic regulation of pyruvate carboxylase is required for immune evasion and pulmonary metastasis",
   "url": "https://www.semanticscholar.org/paper/2e2336e76af165ca51be7702fa689b667363356f"
  }
 ],
 "batch_id": "kaal-review:2026-07-31:streaming-etl-0006",
 "review_provenance": "https://kaal-signal-desk.wulf577462.chatgpt.site/#review",
 "publicationStatus": "public",
 "recordTypeNote": "Dated commentary position extending a scholarly corpus claim. Not a verbatim claim extracted from the paper.",
 "isPartOf": {
  "@id": "https://wulfkaal.github.io/positions/index.json"
 },
 "version": "1.0",
 "canonical_url": "https://wulfkaal.github.io/positions/2026-07-31-6776",
 "canonicalForm": "https://wulfkaal.github.io/positions/2026-07-31-6776.md",
 "candidateId": "kaal:response-draft:2026-07-31:6f4749c3345e6d234f46",
 "evidenceLevel": "abstract indexed",
 "reviewTier": "moderate-confidence claim review",
 "mappingConfidence": 0.3684,
 "mappingAmbiguous": true,
 "mappingMethod": "idf-weighted multi-field mapping v1",
 "mappingWhyRelevant": "Shared high-information concepts: abstract, dynamic, regulation, primary. Scope: hedge fund counterparties are made the primary regulatory targets.",
 "sourceProvenance": {
  "source": "semantic-scholar",
  "sourceRecordId": "2e2336e76af165ca51be7702fa689b667363356f",
  "queryId": "concept:516a267369f9",
  "queryText": "dynamic regulation",
  "canonicalUrl": "https://www.semanticscholar.org/paper/2e2336e76af165ca51be7702fa689b667363356f",
  "doi": "10.1158/1538-7445.advbc23-a053",
  "externalIds": {
   "DOI": "10.1158/1538-7445.advbc23-a053",
   "CorpusId": 267419216,
   "SemanticScholar": "2e2336e76af165ca51be7702fa689b667363356f"
  },
  "retrievedAt": "2026-07-31T13:58:14.237Z",
  "providerPage": 2,
  "rawObservationSha256": "31dff5b1c9e5b7dff972b786945cb710167e70b940a1adff16147001bff8817c",
  "inputSnapshotSha256": "96a846999aefd65306457ebd7971f1abef182a04b39a927618f8460274d795ab",
  "inputLine": 3555,
  "chunkId": "semantic-scholar-00015",
  "workId": "work:doi:10.1158/1538-7445.advbc23-a053",
  "workAuthors": [
   "M. Coleman",
   "E. K. Cotul",
   "Dorothy Teegarden",
   "S. Hursting",
   "Michael K. Wendt"
  ],
  "workPublishedAt": "2024-02-01",
  "identityKeys": [
   "doi:10.1158/1538-7445.advbc23-a053",
   "semantic-scholar:2e2336e76af165ca51be7702fa689b667363356f",
   "url:https://www.semanticscholar.org/paper/2e2336e76af165ca51be7702fa689b667363356f",
   "title:545223b79df61b4b0ad3efa7",
   "proposition:49332eb50c4b1beb294086808444a710f3c97600d9a636d036e6939a53aef918"
  ],
  "sourceProposition": "In contrast, depletion of PC in tumor cells promotes primary tumor growth.",
  "sourcePropositionSha256": "c0b93fed79e72008bac0db0fd6ae85ba2b9fd21d8a254c6a9b29802259cd0a57",
  "sourcePropositionIndex": 2,
  "claimMappings": [
   {
    "claimId": "kaal:claim:3405660-022",
    "claimUrl": "https://wulfkaal.github.io/claims/3405660-022",
    "rank": 1,
    "confidence": 0.3684,
    "method": "idf-weighted multi-field mapping v1",
    "whyRelevant": "Shared high-information concepts: abstract, dynamic, regulation, primary. Scope: hedge fund counterparties are made the primary regulatory targets.",
    "ambiguous": true
   },
   {
    "claimId": "kaal:claim:2831040-015",
    "claimUrl": "https://wulfkaal.github.io/claims/2831040-015",
    "rank": 2,
    "confidence": 0.3613,
    "method": "idf-weighted multi-field mapping v1",
    "whyRelevant": "Shared high-information concepts: abstract, dynamic, regulation, contrast. Scope: review source claim scope.",
    "ambiguous": true
   },
   {
    "claimId": "kaal:claim:4941807-003",
    "claimUrl": "https://wulfkaal.github.io/claims/4941807-003",
    "rank": 3,
    "confidence": 0.3613,
    "method": "idf-weighted multi-field mapping v1",
    "whyRelevant": "Shared high-information concepts: abstract, dynamic, regulation, contrast. Scope: during the development phase of AI technologies; within Web3 governance frameworks.",
    "ambiguous": true
   },
   {
    "claimId": "kaal:claim:2831040-008",
    "claimUrl": "https://wulfkaal.github.io/claims/2831040-008",
    "rank": 4,
    "confidence": 0.358,
    "method": "idf-weighted multi-field mapping v1",
    "whyRelevant": "Shared high-information concepts: abstract, dynamic, regulation, growth. Scope: review source claim scope.",
    "ambiguous": true
   },
   {
    "claimId": "kaal:claim:2470008-014",
    "claimUrl": "https://wulfkaal.github.io/claims/2470008-014",
    "rank": 5,
    "confidence": 0.3506,
    "method": "idf-weighted multi-field mapping v1",
    "whyRelevant": "Shared high-information concepts: abstract, dynamic, regulation, required. Scope: Form PF as adopted by the SEC Division of Investment Management.",
    "ambiguous": true
   }
  ]
 },
 "userAffirmation": "I affirm batch kaal-review:2026-07-31:streaming-etl-0006, SHA-256 d724cb4e85d4ecdf4e8488b6b1c8ed999688fe58732ad5a50c5c197c25427f43, as written and authorize publication of all 250 response claims on my canonical property, preserving their evidence levels, ambiguity labels, provenance, and the unchanged 5,033 scholarly claims.",
 "sha256": "d3b2a9686865c5785ff70cac94d5a61bfae41860486676c1a4891c67d48ae4fa"
}